Welcome to the Prophetic Revelations of Elisha Prabhahar Thompson



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Prophet Explored and Administered so far


Spiritual and its Levels Realm

Financial Realm

Judgement Realm

Medical Realm

Software Engineering and AI Realm

People and Politics Realm

Evil Elimination and Security Realm

Family and Gender Progressiveness Realm

Tolerance among Diversity Realm

  • 19 Nov 25:: Gene Medical Lab Research need the following resources::
  • Few Medical Doctors
  • Few Engineers with UNIX Large file Handling
  • Few Engineers with BioPython AI Handling
  • Few Medical Technicians for Cell Sample Handling
  • DNA Sequencing Machine.
  • Isolating Defect DNA area softwares.
  • Major Analysis would be on High and Low level people Medications Research, Disease Cure through personalised Gene Care with Government Care Cost.
  • Diabetic, Cancer, Eye, Immunity and many medications are addressed sofar up to certain percentage of success from various research centers across the world. Further need to go in depth in research and clinical trials for the outputs before we implement it for millions of people.
  • The Spiritual Loop is cleared and the Material loop need progress. All hospitals and Clinics would implement this with open patient viewable gene medicine.

can i give the same medication of diabetic to different gene protein


No, the same diabetes medication may not be effective for individuals with different genetic variations, even if they have the same clinical diagnosis of diabetes. A patient's genetic makeup significantly influences how they respond to specific medications and dosages. 

The field of pharmacogenomics studies how genes affect a person's response to drugs, and research in diabetes treatment shows that: 

  • Variable Drug Efficacy: For example, over one-third of people with type 2 diabetes do not respond effectively to normal doses of metformin, the first-line medication. A specific genetic variant in the GLUT2 gene, which affects glucose transport, makes individuals respond much better to metformin, while other variants may decrease its effectiveness.
  • Different Mechanisms of Action: Different classes of diabetes medications (e.g., sulfonylureas, GLP-1 analogs) work through different molecular interactions and target different proteins or pathways. A drug designed to target one specific protein or pathway may not work if the patient's condition is primarily caused by a different genetic defect involving another protein.
  • Risk of Side Effects: Genetic variations in drug-metabolizing enzymes (like CYP2C9 for sulfonylureas) can lead to a higher risk of side effects, such as dangerously low blood sugar (hypoglycemia), if the standard dose is used.
  • Monogenic Diabetes: In cases of monogenic diabetes (caused by a single gene mutation, unlike common type 1 or type 2), identifying the specific genetic cause is crucial because some patients can be successfully treated with oral medications instead of insulin, a treatment change that is guided entirely by genetic diagnosis. 

Ultimately, treatment should be tailored to the individual's specific biological cause of high blood sugar and their genetic profile to achieve better outcomes, minimize side effects, and avoid ineffective therapies. This moves medicine away from a "one-size-fits-all" approach toward personalized care. 

Metformin Analysis::  Targets only the following Genes



Gene List 


SLC47A1, PRKAB1, ETFDH



Genei

Gene descriptioni

x

ACACA

Acetyl-CoA carboxylase alpha

ACACB

Acetyl-CoA carboxylase beta

PCCB

Propionyl-CoA carboxylase subunit beta

PRKAA2

Protein kinase AMP-activated catalytic subunit alpha 2

PRKAA1

Protein kinase AMP-activated catalytic subunit alpha 1

PRKAB1

Protein kinase AMP-activated non-catalytic subunit beta 1

PRKAB2

Protein kinase AMP-activated non-catalytic subunit beta 2

PRKAG1

Protein kinase AMP-activated non-catalytic subunit gamma 1

PRKAG3

Protein kinase AMP-activated non-catalytic subunit gamma 3




Genei

Gene descriptioni

x

GPD1

Glycerol-3-phosphate dehydrogenase 1




Metformin comes from a plant called Galega officinalis, known as french lilac or goat’s rueGoat’s rue was first used in medieval Europe to treat a variety of conditions, including worms, seizures, and fever. It was also used to treat symptoms that we associate today with diabetes, including frequent thirst and urination.

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